Milled lactose Pharmaceutical α-lactose monohydrate is mechanically milled to varying degrees of fineness. The available grades differ in their particle size distributions. Because of its fine nature, milled lactose does not tend to flow well, but its relatively high surface area means that it is highly compactable. Milled lactose is therefore used primarily in wet granulation applications for tablets and capsules and for spheres made by extrusion-spheronisation. DFE Pharma offers milled lactose under the product names Lactochem® and Pharmatose®. Lactochem® Fine Powder and Pharmatose® 200M are the DFE Pharma key range products.